- UC Santa Cruz Awarded $2.5M Childhood Cancer Research Grant Fri, Jul 22, 2016
- Ancient Barley Sequencing Study Finds Similarity to Modern Levantine Plants Fri, Jul 22, 2016
- In Brief This Week: Roche; PerkinElmer; Baylor Genetics; and More Fri, Jul 22, 2016
- An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays Fri, Jul 22, 2016
- Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure Fri, Jul 22, 2016
- In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice Fri, Jul 22, 2016
- Manganese in Drinking Water and Cognitive Abilities and Behavior at 10 Years of Age: A Prospective Cohort Study Fri, Jul 22, 2016
- People in the News: Joel Jung, Peter Soparkar, Bernhard Kirschbaum, Oliver Schacht, and Don Hardison Fri, Jul 22, 2016
- German scientist receives lifetime achievement award from American Society for Materials Fri, Jul 22, 2016
- New research to be highlighted at Society of NeuroInterventional Surgery Boston meeting Fri, Jul 22, 2016
- Researchers get new insight into deadly fungal infections Fri, Jul 22, 2016
- Ultrasensitive sensor using N-doped graphene Fri, Jul 22, 2016
- Dynamics of ribosome scanning and recycling revealed by translation complex profiling Wed, Jul 20, 2016
- Replication fork stability confers chemoresistance in BRCA-deficient cells Wed, Jul 20, 2016
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.