- CareDx Settles with Roche Over Allegations of Breach of Agreement Wed, Sep 17, 2014
- Ancient Genome Analysis Indicates Three Ancestral Populations Contributed to Modern-day Europeans Wed, Sep 17, 2014
- NuView, Otsuka Team up to Develop, Commercialize Biomarker for Breast, Prostate Cancer Wed, Sep 17, 2014
- PacBio Long Reads Assess Antibiotic Resistance Plasmids in Wake of Enterobacteriaceae Outbreak Wed, Sep 17, 2014
- Asthma in Inner-City Children at 5-11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort Wed, Sep 17, 2014
- Brain imaging research pinpoints neurobiological basis for key symptoms associated with post-traumatic stress disorder like listlessness and emotional detachment in trauma victims Wed, Sep 17, 2014
- Hubble helps find smallest known galaxy containing a supermassive black hole Wed, Sep 17, 2014
- Scripps Research Institute chemists modify antibiotic to vanquish resistant bacteria Wed, Sep 17, 2014
- Toward making lithium-sulfur batteries a commercial reality for a bigger energy punch Wed, Sep 17, 2014
- Disease models: Statins give bone growth a boost Wed, Sep 17, 2014
- GATM locus does not replicate in rhabdomyolysis study Wed, Sep 17, 2014
- Lethal aggression in Pan is better explained by adaptive strategies than human impacts Wed, Sep 17, 2014
- Plant science: Towards turbocharged photosynthesis Wed, Sep 17, 2014
- Comparative Assessment of the Effects of Climate Change on Heat- and Cold-Related Mortality in the United Kingdom and Australia Mon, Sep 15, 2014
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.