- US Senators Urge Obama Administration to Release FDA Draft Guidance on LDTs Fri, Jul 11, 2014
- Effects of the Endocrine-Disrupting Chemical DDT on Self-Renewal and Differentiation of Human Mesenchymal Stem Cells Fri, Jul 11, 2014
- Residential Greenness and Birth Outcomes: Evaluating the Influence of Spatially Correlated Built-Environment Factors Fri, Jul 11, 2014
- People In The News Fri, Jul 11, 2014
- In Brief This Week: RUCDR Infinite Biologics; Expression Analysis/Quintiles, Illumina; Thermo Fisher; Analytik Jena; Appistry; Acobiom; Genoway Fri, Jul 11, 2014
- Illumina Selected as Preferred Partner for UK's 100,000 Genomes Project Fri, Jul 11, 2014
- Getting a charge out of water droplets Fri, Jul 11, 2014
- Molecular snapshots of oxygen formation in photosynthesis Fri, Jul 11, 2014
- New simple setup for X-ray phase contrast Fri, Jul 11, 2014
- ORNL wins eight R&D 100s Fri, Jul 11, 2014
- Urinary metabolic profiles in early pregnancy are associated with preterm ... - 7thSpace Interactive (press release) Fri, Jul 11, 2014
- Daily Mean Temperature and Clinical Kidney Stone Presentation in Five U.S. Metropolitan Areas: A Time-Series Analysis Thu, Jul 10, 2014
- Neurobiology: Keeping a lid on it Wed, Jul 09, 2014
- Neuroscience: A structure to remember Wed, Jul 09, 2014
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.