- New survey shows 36-percent increase in pediatric patients treated with proton therapy Sat, May 23, 2015
- Note to Readers Fri, May 22, 2015
- House Committee Unanimously Approves Bill Seeking $10B Increase to NIH Funding Fri, May 22, 2015
- A Case–Control Study of Prenatal Thallium Exposure and Low Birth Weight in China Fri, May 22, 2015
- A Unified Probabilistic Framework for Dose–Response Assessment of Human Health Effects Fri, May 22, 2015
- Prepubertal Serum Concentrations of Organochlorine Pesticides and Age at Sexual Maturity in Russian Boys Fri, May 22, 2015
- Vehicular Traffic-Related Polycyclic Aromatic Hydrocarbon Exposure and Breast Cancer Incidence: The Long Island Breast Cancer Study Project (LIBCSP) Fri, May 22, 2015
- Bruker Authorizes Share Buyback Program Fri, May 22, 2015
- People in the News: Charles Wagner, Riccardo Pigliucci, and more Fri, May 22, 2015
- Ames Laboratory intern awarded a NSF Graduate Research Fellowship Fri, May 22, 2015
- Basel physicists develop efficient method of signal transmission from nanocomponents Fri, May 22, 2015
- Visualizing how radiation bombardment boosts superconductivity Fri, May 22, 2015
- Digicel announces its support for the PNG Women in Business Expo - Papua New Guinea Today Wed, May 20, 2015
- 3.3-million-year-old stone tools from Lomekwi 3, West Turkana, Kenya Wed, May 20, 2015
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.