- Goldman Sachs, Leerink Initiate Coverage of T2 Biosystems Tue, Sep 02, 2014
- NIH Offers $5M for Biomarker Studies of Alzheimer's Progression in Down Syndrome Tue, Sep 02, 2014
- Cancer Genetics' Cervical Cancer Test Receives CE Mark Tue, Sep 02, 2014
- Meridian Bio FY 2015 Guidance Below Street Expectations Tue, Sep 02, 2014
- Vaping and Health: What Do We Know about E-Cigarettes? Tue, Sep 02, 2014
- Time after Time: Environmental Influences on the Aging Brain Tue, Sep 02, 2014
- Echoes of Autism? Inhaled Ultrafine Particles and Brain Changes in Mice Tue, Sep 02, 2014
- Hydroxymethylation and Metals: A Potential Epigenetic Marker for Effects of Toxic Exposures Tue, Sep 02, 2014
- Scientists create renewable fossil fuel alternative using bacteria Tue, Sep 02, 2014
- Scripps Florida scientists make diseased cells synthesize their own drug Tue, Sep 02, 2014
- Single laser stops molecular tumbling motion instantly Tue, Sep 02, 2014
- UO-Berkeley Lab unveil new nano-sized synthetic scaffolding technique Tue, Sep 02, 2014
- Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting Sun, Aug 31, 2014
- High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity Sun, Aug 31, 2014
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.