- Varmus Resigns as NCI Director; Plans to Open Research Lab at Weill-Cornell, Assist NY Genome Center Wed, Mar 04, 2015
- Sequenom Posts 13 Percent Rise in Q4 Revenues, Reports Profitability for FY 2014 Wed, Mar 04, 2015
- MPI's Oncology Venture, Lantern Pharma Receive $800K Award to Advance Prostate Cancer Drug Using a Biomarker Wed, Mar 04, 2015
- OpGen Files for IPO for up to $37M Wed, Mar 04, 2015
- Big box stores could ditch the grid, use natural gas fuel cells instead Wed, Mar 04, 2015
- Miscanthus-based ethanol boasts bigger environmental benefits, higher profits Wed, Mar 04, 2015
- Reducing greenhouse gas emissions with a more effective carbon capture method Wed, Mar 04, 2015
- SAS 2015: Call for registration is open Wed, Mar 04, 2015
- A direct GABAergic output from the basal ganglia to frontal cortex Wed, Mar 04, 2015
- Multi-omics of permafrost, active layer and thermokarst bog soil microbiomes Wed, Mar 04, 2015
- Neuroscience: Hot on the trail of temperature processing Wed, Mar 04, 2015
- Temperature representation in the Drosophila brain Wed, Mar 04, 2015
- Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice Tue, Mar 03, 2015
- Maternal Blood Manganese and Early Neurodevelopment: The Mothers and Children’s Environmental Health (MOCEH) Study Tue, Mar 03, 2015
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.