- Brain disease scenarios revised by step-by-step imaging of toxic aggregation Tue, Jul 28, 2015
- UV light can kill foodborne pathogens on certain fruits Tue, Jul 28, 2015
- NIH to Fund Research Testing Cancer Genomics Cloud Pilots Mon, Jul 27, 2015
- Scientists Create CRISPR/Cas9 Knock-In Mutations in Human T Cells Mon, Jul 27, 2015
- Institute Launches to Match Patients With Most Appropriate Drugs Mon, Jul 27, 2015
- Wayne State Awarded $4.8M Grant to Optimize Antibiotic Use for Drug-Resistant Infections Mon, Jul 27, 2015
- Professor Federico Rosei elected ASM International Fellow Mon, Jul 27, 2015
- Smaller, faster, cheaper Mon, Jul 27, 2015
- A self-organized biomechanical network drives shape changes during tissue morphogenesis Mon, Jul 27, 2015
- Regulation of mitochondrial morphology and function by stearoylation of TFR1 Mon, Jul 27, 2015
- Desert Dust Outbreaks in Southern Europe: Contribution to Daily PM10 Concentrations and Short-Term Associations with Mortality and Hospital Admissions Fri, Jul 24, 2015
- Environmental Chemicals in Urine and Blood: Improving Methods for Creatinine and Lipid Adjustment Fri, Jul 24, 2015
- Satellite-Based Spatiotemporal Trends in PM2.5 Concentrations: China, 2004–2013 Fri, Jul 24, 2015
- Biogenesis and structure of a type VI secretion membrane core complex Wed, Jul 22, 2015
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.