- ASCO Issues New Clinical Practice Guideline for Women With Certain Breast Cancers Mon, Feb 08, 2016
- Exiqon Q4 Revenues Jump 36 Percent Mon, Feb 08, 2016
- Akesogen Lands CAP Accreditation Mon, Feb 08, 2016
- Team Presents Proof-of-Principle TWAS for Obesity-Relevant Traits Mon, Feb 08, 2016
- A disposable, highly sensitive biosensing system Mon, Feb 08, 2016
- Device hits pancreatic tumors hard with toxic 4-drug cocktail, sparing the body Mon, Feb 08, 2016
- Oregano may reduce methane in cow burps Mon, Feb 08, 2016
- Physics: It's happening inside your body right now Mon, Feb 08, 2016
- Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer Mon, Feb 08, 2016
- The peptidergic control circuit for sighing Mon, Feb 08, 2016
- Associations of Residential Long-Term Air Pollution Exposures and Satellite-Derived Greenness with Insulin Resistance in German Adolescents Fri, Feb 05, 2016
- Key Elements for Judging the Quality of a Risk Assessment Fri, Feb 05, 2016
- Long-Term Air Pollution and Traffic Noise Exposures and Mild Cognitive Impairment in Older Adults: A Cross-Sectional Analysis of the Heinz Nixdorf Recall Study Fri, Feb 05, 2016
- Transgenic Overexpression of Aryl Hydrocarbon Receptor Repressor (AhRR) and AhR-Mediated Induction of CYP1A1, Cytokines, and Acute Toxicity Fri, Feb 05, 2016
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.