- Wells Fargo Initiates Coverage of Foundation Medicine, Myriad Genetics, Genomic Health Fri, Dec 19, 2014
- FDA Approves Myriad's BRACAnalysis CDx for Use with Ovarian Cancer Drug Fri, Dec 19, 2014
- Title: Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort Fri, Dec 19, 2014
- Title: Developmental Exposure to a Commercial PBDE Mixture: Effects on Protein Networks in the Cerebellum and Hippocampus of Rats Fri, Dec 19, 2014
- People in the News Fri, Dec 19, 2014
- New Products Posted to GenomeWeb Fri, Dec 19, 2014
- Atom-thick CCD could capture images Fri, Dec 19, 2014
- NASA's SDO captures images of 2 mid-level flares Fri, Dec 19, 2014
- Quantum world without queues could lead to better solar cells Fri, Dec 19, 2014
- The state of shale Fri, Dec 19, 2014
- Title: Autism Spectrum Disorder and Particulate Matter Air Pollution before, during, and after Pregnancy: A Nested Case–Control Analysis within the Nurses’ Health Study II Cohort Thu, Dec 18, 2014
- 2014 Editors' choice Wed, Dec 17, 2014
- Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis Wed, Dec 17, 2014
- Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions Wed, Dec 17, 2014
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.