- Potential migraine therapy to be presented April 22 by Achelios Therapeutics Sat, Apr 18, 2015
- Study reveals a cause of poorer outcomes for African-American patients with breast cancer Sat, Apr 18, 2015
- Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Thyroid Hormones in Maternal and Cord Sera: The HOME Study, Cincinnati, USA Fri, Apr 17, 2015
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- The big medical data miss: challenges in establishing an open medical resource - Nature.com Fri, Apr 17, 2015
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- Fruit fly studies shed light on adaptability of nerve cells Fri, Apr 17, 2015
- Toward Precision Medicine - Harvard Magazine Wed, Apr 15, 2015
- Que prévoit la loi santé en matière d'alimentation et d'environnement ? - Bio à la Une.com Wed, Apr 15, 2015
- A Mercury-like component of early Earth yields uranium in the core and high mantle 142Nd Wed, Apr 15, 2015
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The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.