- Singapore Launches Diagnostics Development Hub Wed, Nov 26, 2014
- NIH to Fund Coordination Center for Alzheimer's Research Wed, Nov 26, 2014
- Q&A: Clinical Microbiology Lab Director Nathan Ledeboer on MDx Trends Wed, Nov 26, 2014
- PositiveID to Issue $4M in Senior Notes to Investor Wed, Nov 26, 2014
- Matched 'hybrid' systems may hold key to wider use of renewable energy Wed, Nov 26, 2014
- NASA's Van Allen Probes spot an impenetrable barrier in space Wed, Nov 26, 2014
- Particles, waves and ants Wed, Nov 26, 2014
- Stanford engineers invent high-tech mirror to beam heat away from buildings into space Wed, Nov 26, 2014
- Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens Wed, Nov 26, 2014
- Immunology: Tolerance lies in the timing Wed, Nov 26, 2014
- MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer Wed, Nov 26, 2014
- MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae Wed, Nov 26, 2014
- Title: Associations of Plasma Concentrations of Dichlorodiphenyldichloroethylene and Polychlorinated Biphenyls with Prostate Cancer: A Case–Control Study in Guadeloupe (French West Indies) Fri, Nov 21, 2014
- Title: Exposure to Free and Conjugated Forms of Bisphenol A and Triclosan among Pregnant Women in the MIREC Cohort Fri, Nov 21, 2014
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.