- NCCN Including Use of VeriStrat in NSCLC Guidelines Fri, Oct 24, 2014
- Amoy Diagnostics Obtains CE Mark for Cancer Mutation Assays Fri, Oct 24, 2014
- In Brief This Week: Sequenta, Celegene; Thermo Fisher; Quidel, Life Technologies; Hitachi, OpGen; PerkinElmer; Sigma-Aldrich; More Fri, Oct 24, 2014
- People In The News Fri, Oct 24, 2014
- Title: Building a Robust 21st Century Chemical Testing Program at the U.S. Environmental Protection Agency: Recommendations for Strengthening Scientific Engagement Fri, Oct 24, 2014
- Title: Cadmium and Proliferation in Human Uterine Leiomyoma Cells: Evidence of a Role for EGFR/MAPK Pathways but Not Classical Estrogen Receptor Pathways Fri, Oct 24, 2014
- Title: Monitoring Indoor Exposure to Organophosphate Flame Retardants: Hand Wipes and House Dust Fri, Oct 24, 2014
- Title: Use of Satellite Observations for Long-Term Exposure Assessment of Global Concentrations of Fine Particulate Matter Fri, Oct 24, 2014
- New findings will improve the sex lives of women with back problems Fri, Oct 24, 2014
- New hope for drug discovery in African sleeping sickness Fri, Oct 24, 2014
- New methods for maintaining the quality of minimally processed potatoes for 14 days Fri, Oct 24, 2014
- Three-dimensional metamaterials with a natural bent Fri, Oct 24, 2014
- Dendritic cells control fibroblastic reticular network tension and lymph node expansion Wed, Oct 22, 2014
- Developmental biology: Cells unite by trapping a signal Wed, Oct 22, 2014
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.