- Rare Variants Influence COPD Risk, Targeted Sequencing Study Finds Tue, Jan 24, 2017
- NSF, USDA Award Microbiome Research Grants Tue, Jan 24, 2017
- Metagenomic Sequence Data Improves Protein Modeling Tue, Jan 24, 2017
- Novacyt 2016 Revenues Up 25 Percent Tue, Jan 24, 2017
- An urban collection of modern-day micrometeorites Tue, Jan 24, 2017
- Finnish biopharmaceutical company Desentum closes financial round totalling nearly EUR 2 Million Tue, Jan 24, 2017
- New insights into the forms of metal-organic frameworks Tue, Jan 24, 2017
- UAB and VICIS announce partnership to deliver safer football helmets Tue, Jan 24, 2017
- Erratum: “A Retrospective Assessment of Occupational Exposure to Elemental Carbon in the U.S. Trucking Industry” Mon, Jan 23, 2017
- Erratum: “Para– and Ortho-Substitutions Are Key Determinants of Polybrominated Diphenyl Ether Activity toward Ryanodine Receptors and Neurotoxicity” Mon, Jan 23, 2017
- An Argonaute phosphorylation cycle promotes microRNA-mediated silencing Mon, Jan 23, 2017
- MATRILINEAL, a sperm-specific phospholipase, triggers maize haploid induction Mon, Jan 23, 2017
- MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion Mon, Jan 23, 2017
- Weak synchronization and large-scale collective oscillation in dense bacterial suspensions Mon, Jan 23, 2017
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.