- Australian Partners Link up With Fluidigm to Open Single-Cell Genomics Center Thu, Sep 03, 2015
- Exome Sequencing Uncovers Monogenic Condition Marked By Speech Problems, Intellectual Delay Thu, Sep 03, 2015
- Quest Subsidiary Lands FDA Clearance for Herpes Test From Genital Swabs Thu, Sep 03, 2015
- OGT Transfers NGS Services to Source BioScience, Will Focus on Genomic Products Thu, Sep 03, 2015
- Hubble survey unlocks clues to star birth in neighboring galaxy Thu, Sep 03, 2015
- Multi-million pound project to use nanotechnology to improve safety Thu, Sep 03, 2015
- Mutation protects plants against harmful explosive, TNT Thu, Sep 03, 2015
- Potential of disk-shaped small structures, coccoliths Thu, Sep 03, 2015
- Evolutionary biology: Perplexing effects of phenotypic plasticity Wed, Sep 02, 2015
- Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth Wed, Sep 02, 2015
- Global separation of plant transpiration from groundwater and streamflow Wed, Sep 02, 2015
- Real-time observation of the initiation of RNA polymerase II transcription Wed, Sep 02, 2015
- Going Deep: Cautious Steps toward Seabed Mining Tue, Sep 01, 2015
- Letter from the New Editor-in-Chief: My Perspective on Environmental Health Perspectives Tue, Sep 01, 2015
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.