To learn more see below:
- InsP7 Is a Small-molecule Regulator of NUDT3-mediated MRNA Decapping and Processing-body Dynamics
- Association of Preeclampsia in Term Births With Neurodevelopmental Disorders in Offspring
- Deletion of Topoisomerase 1 in Excitatory Neurons Causes Genomic Instability and Early Onset Neurodegeneration
- Unique MicroRNA Alterations in Hepatocellular Carcinomas Arising Either Spontaneously or Due to Chronic Exposure to Ginkgo Biloba Extract (GBE) in B6C3F1/N Mice
- HNF4alpha Regulates Sulfur Amino Acid Metabolism and Confers Sensitivity to Methionine Restriction in Liver Cancer
- Improved Asthma Outcomes Observed in the Vicinity of Coal Power Plant Retirement, Retrofit and Conversion to Natural Gas
- A Comprehensive Analysis of Racial Disparities in Chemical Biomarker Concentrations in United States Women, 1999-2014
- Urine Tungsten and Chronic Kidney Disease in Rural Colorado
- Watching a Double Strand Break Repair Polymerase Insert a Pro-Mutagenic Oxidized Nucleotide
- UDP-Glucose and P2Y14 Receptor Amplify Allergen-Induced Airway Eosinophilia
- Autophagy of the M6A mRNA Demethylase FTO Is Impaired by Low-level Arsenic Exposure to Promote Tumorigenesis
- Prenatal Phthalate Exposures and Executive Function in Preschool Children
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.