- Better metric for thermoelectric materials means better design strategies
- Developmental Exposures to Perfluorooctanesulfonic Acid (PFOS) Impact Embryonic Nutrition, Pancreatic Morphology, and Adiposity in the Zebrafish, Danio Rerio
- LIG1 Syndrome Mutations Remodel a Cooperative Network of Ligand Binding Interactions to Compromise Ligation Efficiency
- X-ray study recasts role of battery material from cathode to catalyst
- Vaping vs. smoking: Impact on cells compared
- A lightweight and durable radiator for cooling electric vehicle batteries
- Glass injection molding
- To nodulate or not? Uncovering how nitrate regulates gene expression in legumes
- An on-off switch for gene editing
- Pillar of support: Breakthrough discovery could speed up bone implant recovery
- Brain organoids uncover various mechanisms of virus-induced microcephaly
- The European Hexa-X project for the development of 6G technology starts
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.