New book on the exposome coming in Summer, 2020
- Brief bursts, big insights
- Computer simulations visualize how DNA is recognized to convert cells into stem cells
- Cobalt-based catalysts promise to enhance heavy oil extraction
- Iodide salts stabilise biocatalysts for fuel cells
- ESO telescope sees surface of dim Betelgeuse
- Longstanding flaw in sensor readings could lead to heating and cooling design errors
- Gold nanoclusters: new frontier for developing medication for treatment of Alzheimer’s disease
- Five women scientists in developing countries win 2020 OWSD-Elsevier Foundation Awards
- TPU researchers discover how to improve safety of nuclear power plants
- Galactic cosmic rays affect Titan’s atmosphere
- Dartmouth’s Chenfeng Ke wins Cram Lehn Pedersen Prize
- The catalyst that removes CO2 and produces hydrocarbons
The human exposome is the environmental equivalent of the human genome. It is a representation of the complex exposures we are subjected to throughout our lives, including our diet, lifestyle factors, and social influences. It also incorporates how our bodies respond to these challenges. The exposome encompasses much of what we refer to as nurture. The term exposome was coined by Dr. Christopher Wild at the International Agency for Research on Cancer, World Health Organization.
Several academic and government laboratories across the world are collecting data that can contribute to our understanding of the exposome. Our goal is to bring these investigators together to formulate a plan to define the exposome in a way that is useful to those in health care and public health, to identify gaps in knowledge or technique, and to help develop a new generation of scientists who focus on these complex environmental influences on health. The Human Exposome Project will build upon the already existing resources and work to identify additional funding to pursue the important questions in the field.
The rapid advancement in the areas of genetics and genomics has transformed our understanding of human biology. However, genome-wide association studies (GWAS) have only been able to account for a minority of disease risk. Quantitative data on the environmental factors that influence health are desperately needed. The Human Exposome Project can help provide this important information in a form that can be used to directly impact human health.