Archives: News

“Taking on the Exposome”

Biomedical Computation Review recently published “Taking on the Exposome: Bringing Bioinformatics Tools to the Environmental Side of the Health Equation.” Kristin Sainani, PhD, reviews progress in exposome research, including recent Environment-Wide Association Studies and novel data collection techniques, as well as significant remaining challenges in collecting, analyzing, and interpreting exposome data.  The article concludes with […]

NIEHS Exposome Webinar: Tooth Matrix Biomarkers

On Tuesday, July 26th from 11:00AM-12:30PM, Manish Arora of Mount Sinai’s School of Medicine will present their work developing tooth matrix biomarkers for environmental health research. Their research offers the potential to capture exposures that have occurred during critical developmental periods in utero. See our previous highlight discussing the importance of their work to the […]

Filling the need for comprehensive toxicity data

A continued challenge for regulatory agencies and environmental health research is a lack of toxicity information for the majority of chemicals present in consumer products and used in other applications. Regulatory agencies and researchers have been working to fill this information gap. The National Institute of Health’s Tox21 initiative is one case where high throughput […]

The Exposome’s 10th Year in Review

The momentum of exposome research is building with each of the past few years offering advancements to the conversation, technologies, analytic methods, funding opportunities, etc. The past year was no exception. Exposome Gaining Attention January 2015 kicked off with an NIEHS (National Institute of Environmental Health Sciences) sponsored workshop on the exposome. Pre-meeting and at-meeting […]

Capturing Genome x Exposome Interactions

As the push for exposome research grows, more examples are needed of studies that have successfully captured cumulative exposures and related biological responses while considering the baseline genetic background. In a recent paper published in Current Environmental Health Reports, Chirag Patel, publisher of the first environmental-wide association study (EWAS), describes the challenges of exposome characterization […]

Mutagenesis highlights exposomics research

In this month’s issue of Mutagenesis, the journal highlights exposomics in a special topic series. Dr. Paolo Vineis,director of the European EXPOsOMICS project, introduces the series with his commentary, Exposomics: mathematics meets biology. Dr. Vineis emphasizes that a proof-of-principle for exposome research has so far been lacking. Through the Mutagenesis series, the authors aim to help fill that gap through […]

Promising new biomarker to retrospectively capture the early-life exposome

Prenatal and early childhood exposures are recognized as playing a significant role in later health outcomes. With key developmental windows during the prenatal period and the first couple years of life, there is increased interest in studying the early-life exposome. Investments in research are continuing to increase. In 2013, HELIX: The Human Early-Life Exposome was funded […]

National Institutes of Health awards ~$49 million to contribute to studies of the early-life exposome

Early this week the National Institute of Health revealed the awards for the Children’s Health Exposure Analysis Resource (CHEAR), a research initiative that will facilitate the implementation of the exposome concept into children’s health studies. Under the direction of the National Institute of Environmental Health Sciences (NIEHS), CHEAR will provide laboratory and data analysis services to […]